CRC 779

Neurobiology of Motivated Behavior

Relevant CRC 779 Publications

Project A01

  • Bartsch M, Boehler CN, Stoppel C, Merkel C, Heinze HJ, Schoenfeld MA, Hopf JM (2014) Determinants of global color-based selection in human visual cortex. Cerebral Cortex (doi:10.1093/cercor/bhu078).
  • Boehler CN, Schoenfeld MA, Heinze H-J, Hopf J-M (2010) Object-based selection of irrelevant features is not confined to the attended object. Journal of Cognitive Neuroscience (in press).
  • Boehler CN, Hopf JM, Krebs RM, Stoppel CM, Schoenfeld MA, Heinze HJ, Noesselt T (2011b) Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward. Journal of Neuroscience 31:4955-4961.
  • Boehler CN, Bunzeck N, Krebs RM, Noesselt T, Schoenfeld MA, Heinze HJ, Munte TF, Woldorff MG, Hopf JM (2011c) Substantia Nigra Activity Level Predicts Trial-to-Trial Adjustments in Cognitive Control. J Cogn Neurosci 23:362-373.
  • Boehler CN, Hopf JM, Stoppel CM, Krebs RM (2012) Motivating inhibition - reward prospect speeds up response cancellation. Cognition 125:498-503.
  • Boehler CN, Schevernels H, Hopf JM, Stoppel CM, Krebs RM (2014) Reward prospect rapidly speeds up response inhibition via reactive control. Cogn Affect Behav Neurosci 14:593-609.
  • Buschschulte A, Boehler CN, Strumpf H, Stoppel CM, Schoenfeld MA, Hopf JM (submitted) Dissociating reward- and attention-related biasing of sensory selection in visual cortex.
  • Buschschulte A, Boehler CN, Strumpf H, Stoppel C, Heinze HJ, Schoenfeld MA, Hopf JM (2014) Reward- and Attention-related Biasing of Sensory Selection in Visual Cortex. J Cogn Neurosci 26:1049–1065.
  • Hopf JM, Schoenfeld MA, Buschschulte A, Rautzenberg A, Krebs RM, Boehler CN (2015) The modulatory impact of reward and attention on global feature selection in human visual cortex. Visual Cognition 23:229-248.
  • Krebs RM, Hopf JM, Boehler CN (2015) Within-trial effects of stimulus-reward associations. In: Motivation and Cognitive Control (Braver T, ed). New York: Psychology Press (in press).
  • Merkel C, Stoppel CM, Hillyard SA, Heinze HJ, Hopf JM, Schoenfeld MA (2014) Spatio-temporal patterns of brain activity distinguish strategies of multiple-object tracking. J Cogn Neurosci 26:28-40.
  • Merkel C, Hopf JM, Heinze HJ, Schoenfeld MA Neural correlates of multiple object tracking strategies. (2015) NeuroImage (in press)
  • Schoenfeld MA, Hopf JM, Merkel C, Heinze HJ, Hillyard SA (2014) Object-based attention involves the sequential activation of feature-specific cortical modules. Nat Neurosci 17:619-624.
  • Stoppel CM, Boehler CN, Strumpf H, Heinze HJ, Hopf JM, Schoenfeld MA (2011) Neural processing of reward magnitude under varying attentional demands. Brain Res 1383:218-229.
  • Stoppel CM, Boehler CN, Strumpf H, Heinze HJ, Hopf JM, Duzel E, Schoenfeld MA (2009) Neural correlates of exemplar novelty processing under different spatial attention conditions. Human Brain Mapping 30:3759-3771.

Project A02

  • Deserno L, Huys QJ, Boehme R, Buchert R, Heinze HJ, Grace AA, Dolan RJ, Heinz A, Schlagenhauf F (2015) Ventral striatal dopamine reflects behavioral and neural signatures of model-based control during sequential decision making. Proc Natl Acad Sci U S A 112:1595-600.
  • Dürschmid S, Zaehle T, Hinrichs H, Heinze HJ, Voges J, Garrido M, Dolan R & Knight RT (2015) Sensory Deviancy Detection measured directly within Human Nucleus Accumbens. Cerebral Cortex [Epub ahead of print]
  • Duzel, E., Bunzeck, N., Guitart-Masip, M., & Duzel, S. (2010). NOvelty-related motivation of anticipation and exploration by dopamine (NOMAD): implications for healthy aging. Neurosci Biobehav Rev, 34, 660-669.
  • Guitart-Masip M, Fuentemilla L, Bach DR, Huys QJ, Dayan P, Dolan RJ, Duzel E (2011) Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain. J Neurosci 31:7867-75.
  • Guitart-Masip M, Chowdhury R, Sharot T, Dayan P, Duzel E, Dolan RJ (2012) Action controls dopaminergic enhancement of reward representations. Proc Natl Acad Sci U S A.109: 7511-6.
  • Guitart-Masip M Duzel E, Dolan R, Dayan P (2014) Action versus valence in decision making. Trends Cogn Sci. 18:194-202.
  • Heinze HJ, Heldmann M, Voges J, Hinrichs H, Marco-Pallares J, Hopf JM, Müller UJ, Galazky I, Sturm V, Bogerts B, Münte TF (2009) Counteracting incentive sensitization in severe alcohol dependence using deep brain stimulation of the nucleus accumbens: clinical and basic science aspects. Front Hum Neurosci 3:22
  • Knight RT, Heinze HJ (2008) The human brain: the final journey. Front Neurosci 2:15-6.
  • Münte TF, Heldmann M, Hinrichs H, Marco-Pallares J, Krämer UM, Sturm V, Heinze HJ (2008) Contribution of subcortical structures to cognition assessed with invasive electrophysiology in humans. Front Neurosci 2:72-8.
  • Münte TF, Heldmann M, Hinrichs H, Marco-Pallares J, Krämer UM, Sturm V, Heinze HJ (2007) Nucleus Accumbens is Involved in Human Action Monitoring: Evidence from Invasive Electrophysiological Recordings.Front Hum Neurosci 1:11.
  • Schott BH, Niehaus L, Wittmann BC, Schütze H, Seidenbecher CI, Heinze HJ, Düzel E (2007) Ageing and early-stage Parkinson`s disease affect separable neural mechanisms of mesolimbic reward processing. Brain 130:2412-2424.
  • Stenner MP, Litvak V, Rutledge RB, Zaehle T, Schmitt FC, Voges J, Heinze HJ, Dolan RJ. (2015a) Cortical drive of low-frequency oscillations in the human nucleus accumbens during action selection. J Neurophysiol. [Epub ahead of print]
  • Stenner MP, Rutledge RB, Zaehle T, Schmitt FC, Kopitki, K, Kowski, AB, Voges J, Heinze HJ, Dolan RJ. (2015b) No unified reward prediction error in local field potentials from the human nucleus accumbens: evidence from epilepsy patients. J Neurophysiol. [Epub ahead of print]
  • Sweeney-Reed CM, Zaehle T, Voges J, Schmitt FC, Buentjen L, Kopitzki K, Esslinger C, Hinrichs H, Heinze HJ, Knight RT & Richardson-Klavehn A. (2014) Corticothalamic phase synchrony and cross-frequency coupling predict human memory formation. eLife doi: 10.7554/eLife.05352
  • Sweeney-Reed CM, Zaehle T, Voges J, Schmitt FC, Buentjen L, Kopitzki K, Hinrichs H, Heinze HJ, Rugg MD, Knight RT, Richardson-Klavehn A. (2015). Thalamic theta phase alignment predicts human memory formation and anterior thalamic cross-frequency coupling. eLife. doi: 10.7554/eLife.07578.
  • Wagenbreth C*, Zaehle T*, Galazky I, Voges J, Guitart-Masip M, Heinze HJ & Duzel E (2015) (* shared first authorship) Deep brain stimulation of the subthalamic nucleus modulates reward processing and action selection in Parkinson patients. J Neurol. [Epub ahead of print]
  • Zaehle T, Bauch EM, Hinrichs H, Schmitt FC, Voges J, Heinze HJ & Bunzeck N (2013) Nucleus accumbens activity dissociates different forms of salience: evidence from human intracranial recordings. J Neuroscience 33: 8764-71.

Project A03

  • Azanon E, Stenner MP, Cardini F, Haggard P (2015) Dynamic tuning of tactile localization to body posture. Curr Biol 25:512-517.
  • Bauer M, Stenner MP, Friston KJ, Dolan RJ (2014) Attentional modulation of alpha/beta and gamma oscillations reflect functionally distinct processes. J Neurosci 34:16117-16125.
  • Bles M, Haynes JD (2008) Detecting concealed information using brain-imaging technology. Neurocase 14:82-92.
  • Boehler CN, Hopf JM, Krebs RM, Stoppel CM, Schoenfeld MA, Heinze HJ, Noesselt T (2011a) Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward. J Neurosci 31:4955-4961.
  • Boehler CN, Bunzeck N, Krebs RM, Noesselt T, Schoenfeld MA, Heinze HJ, Munte TF, Woldorff MG, Hopf JM (2011b) Substantia nigra activity level predicts trial-to-trial adjustments in cognitive control. J Cogn Neurosci 23:362-373.
  • Bonath B, Tyll S, Budinger E, Krauel K, Hopf JM, Noesselt T (2013) Task-demands and audio-visual stimulus configurations modulate neural activity in the human thalamus. NeuroImage 66:110-118.
  • Haynes JD (2009) Decoding visual consciousness from human brain signals. Trends Cogn Sci 13:194-202.
  • Haynes JD (2011) Multivariate decoding and brain reading: Introduction to the special issue. Neuroimage 56:385-386.
  • Heimrath K, Breitling C, Krauel K, Heinze HJ, Zaehle T (2015) Modulation of pre-attentive spectro-temporal feature processing in the human auditory system by HD-tDCS. European Journal of Neuroscience doi: 10.1111/ejn.12908.
  • Kahnt T, Heinzle J, Park SQ, Haynes JD (2010) The neural code of reward anticipation in human orbitofrontal cortex. Proc Natl Acad Sci U S A 107:6010-6015.
  • Kahnt T, Grueschow M, Speck O, Haynes JD (2011) Perceptual learning and decision-making in human medial frontal cortex. Neuron 70:549-559.
  • Krauel K, Duzel E, Hinrichs H, Lenz D, Herrmann CS, Santel S, Rellum T, Baving L (2009) Electrophysiological correlates of semantic processing during encoding of neutral and emotional pictures in patients with ADHD. Neuropsychologia 47:1873-1882.
  • Krauel K, Feldhaus HC, Simon A, Rehe C, Glaser M, Flechtner HH, Heinze HJ, Niehaus L (2010) Increased echogenicity of the substantia nigra in children and adolescents with attention-deficit/hyperactivity disorder. Biol Psychiatry 68:352-358.
  • Lenz D, Krauel K, Flechtner HH, Schadow J, Hinrichs H, Herrmann CS (2010) Altered evoked gamma-band responses reveal impaired early visual processing in ADHD children. Neuropsychologia 48:1985-1993.
  • Prehn-Kristensen A, Krauel K, Hinrichs H, Fischer J, Malecki U, Schuetze H, Wolff S, Jansen O, Duezel E, Baving L (2011) Methylphenidate does not improve interference control during a working memory task in young patients with attention-deficit hyperactivity disorder. Brain Res 1388:56-68.
  • Soon CS, Brass M, Heinze HJ, Haynes JD (2008) Unconscious determinants of free decisions in the human brain. Nat Neurosci 11:543-545.
  • Stenner MP, Bauer M, Heinze HJ, Haggard P, Dolan RJ (2015a) Parallel processing streams for motor output and sensory prediction during action preparation. Journal of Neurophysiology 113:1752-1762.
  • Stenner MP, Bauer M, Machts J, Heinze HJ, Haggard P, Dolan RJ (2014b) Re-construction of action awareness depends on an internal model of action-outcome timing. Consciousness and Cognition 25:11-16.
  • Stenner MP, Bauer M, Sidarus N, Heinze HJ, Haggard P, Dolan RJ (2014c) Subliminal action priming modulates the perceived intensity of sensory action consequences. Cognition 130:227-235.
  • Stenner MP, Litvak V, Rutledge RB, Zaehle T, Schmitt FC, Voges J, Heinze HJ, Dolan RJ (2015b) Cortical drive of low-frequency oscillations in the human nucleus accumbens during action selection. Journal of Neurophysiology:jn 00988 02014.
  • Tegelbeckers J, Bunzeck N, Duzel E, Bonath B, Flechtner HH, Krauel K (2015) Altered salience processing in attention deficit hyperactivity disorder. Human Brain Mapping 36:2049-2060.
  • Thome J, Ehlis AC, Fallgatter AJ, Krauel K, Lange KW, Riederer P, Romanos M, Taurines R, Tucha O, Uzbekov M, Gerlach M (2012) Biomarkers for attention-deficit/hyperactivity disorder (ADHD). A consensus report of the WFSBP task force on biological markers and the World Federation of ADHD. World J Biol Psychiatry 13:379-400.

Project A04

  • Annac E, Manginelli AA, Pollmann S, Shi Z, Müller HJ, Geyer T (2013) Memory under pressure: secondary-task effects on contextual cueing of visual search. Journal of Vision,13(13): 6.
  • Burzynska AZ, Garrett DD, Preuschhof C, Nagel IE, Li SC, Bäckman L, Heekeren HR. Lindenberger U (2013) A scaffold for efficiency in the human brain. The Journal of Neuroscience 33:17150-17159.
  • Daniel R, Pollmann S (2010) Comparing the neural basis of monetary reward and cognitive feedback during infor-mation-integration category learning. J Neurosci 30(1): 47–55.
  • Daniel R, Pollmann S (2012). Striatal activations signal prediction errors on confidence in the absence of external feedback. NeuroImage 59:.3457-3467.
  • Daniel R, Pollmann S (2014) A universal role of the ventral striatum in reward-based learning: Evidence from human studies. Neurobiology of Learning and Memory 114:90-100.
  • Daniel R, Wagner G, Koch K, Reichenbach JR, Sauer H, Schlösser RG (2011). Assessing the neural basis of uncertainty in perceptual category learning through varying levels of distortion. J Cognit Neurosci, 23(7): 1781-1793.
  • Garrett DD, Nagel IE, Preuschhof C, Burzynska AZ, Marchner J, Wiegert S, Jungehülsing G, Nyberg L, Villringer A, Li SC, Heekeren HR, Bäckman L, Lindenberger U (2015) Amphetamine Modulates Brain Signal Variability and Working Memory in Younger and Older Adults. Proceedings of the National Academy of Sciences. pii:201504090
  • Geyer T, Baumgartner F, Müller HJ, Pollmann S (2012) Medial temporal lobe-dependent repetition suppression and enhancement due to implicit vs. explicit processing of individual repeated search displays. Frontiers in Human Neuroscience 6:272. doi: 10.3389/fnhum.2012.00272.
  • Hanke M, Halchenko YO, Haxby JV, Pollmann S (2010). Statistical learning analysis in neuroscience: aiming for transparency. Front Neurosci 4: 38-43.
  • Hanke M, Halchenko YO, Sederberg PB, Hanson SJ, Haxby JV, Pollmann S (2009) PyMVPA: A Python toolbox for multivariate pattern analysis of fMRI data. Neuroinformatics 7: 37-53.
  • Manginelli AA, Geringswald F, Pollmann S (2011) Visual search facilitation in repeated displays depends on visuospatial working memory, Exp Psychol, im Druck.
  • Manginelli AA, Baumgartner F, Pollmann S (2013) Dorsal and ventral working memory-related brain areas support distinct processes in contextual cueing. Neuroimage 67:363-374.
  • Manginelli AA, Langer N, Klose D, Pollmann S (2013) Contextual cueing under working memory load: Selective interference of visuospatial load with expression of learning. Attention, Perception, & Psychophysics 75:1103-1117
  • Nagel IE, Preuschhof C, Li SC, Nyberg L, Bäckman L, Lindenberger U, Heekeren HR (2009) Performance level modulates adult age differences in brain activation during spatial working memory. Proceedings of the National Academy of Sciences 106:22552-22557.
  • Nagel IE, Preuschhof C, Li SC, Nyberg L, Bäckman L, Lindenberger U, Heekeren, HR (2011) Load modulation of BOLD response and connectivity predicts working memory performance in younger and older adults. Journal of Cognitive neuroscience 23:2030-2045.
  • Pollmann S, Manginelli AA (2009) Anterior prefrontal involvement in implicit contextual change detection. Front Hum Neurosci 3:28.

Project A06

  • Abler B, Gron G, Hartmann A, Metzger C, Walter M (2012) Modulation of Frontostriatal Interaction Aligns with Reduced Primary Reward Processing under Serotonergic Drugs. J Neurosci 32:1329-1335.
  • Bermpohl F, Walter M, Sajonz B, Lücke C, Hägele C, Sterzer P, Adli M, Heinz A, Northoff G. Attentional modulation of emotional stimulus processing in patients with major depression--alterations in prefrontal cortical regions. Neurosci Lett. 2009 Oct 2;463(2):108-13.
  • Bernstein HG, Tausch A, Wagner R, Steiner J, Seeleke P, Walter M, Dobrowolny H, Bogerts B (2013) Disruption of Glutamate-Glutamine-GABA Cycle Significantly Impacts on Suicidal Behaviour: Survey of the Literature and Own Findings on Glutamine Synthetase. CNS Neurol Disord Drug Targets.
  • Bielau H, Steiner J, Mawrin C, Träubner K, Brisch R, Meyer-Lotz G, Brodhun M, Dobrowolny H, Baumann B, Gos T, Bernstein HG, Bogerts B. Dysregulation of GABAergic neurotransmission in mood disorders: a postmortem study. Ann N Y Acad Sci. 2007 Jan;1096:157-69.
  • Davydova D, Marini C, King C, Klueva J, Bischof F, Romorini S, Montenegro-Venegas C, Heine M, Schneider R, Schröder MS, Altrock WD, Henneberger C, Rusakov DA, Gundelfinger ED, Fejtova A (2014) Bassoon specifically controls presynaptic P/Q-type Ca2+ channels via RIM-binding protein. Neuron 82:181-194.
  • Dou W, Palomero-Gallagher N, van Tol M-J, Kaufmann J, Zhong K, Bernstein H-G, Heinze H-J, Speck O, Walter M (2013) Systematic regional variations of GABA, glutamine, and glutamate concentrations follow receptor fingerprints of human cingulate cortex. J Neurosci 33:12698-12704.
  • Gos T, Krell D, Bielau H, Steiner J, Mawrin C, Träubner K, Brisch R, Bernstein HG, Jankowski Z, Bogerts B. Demonstration of disturbed activity of the lateral amygdaloid nucleus projection neurons in depressed patients by the AgNOR staining method. J Affect Disord. 2010 Nov;126(3):402-10.
  • Gos T, Günther K, Bielau H, Dobrowolny H, Mawrin C, Trübner K, Brisch R, Steiner J, Bernstein HG, Jankowski Z, Bogerts B. Suicide and depression in the quantitative analysis of glutamic acid decarboxylase-Immunoreactive neuropil. J Affect Disord. 2009 113:45-1155.
  • Horn DI, Yu C, Steiner J, Buchmann J, Kaufmann J, Osoba A, Eckert U, Zierhut KC, Schiltz K, He H, Biswal B, Bogerts B, Walter M. Glutamatergic and resting-state functional connectivity correlates of severity in major depression - the role of pregenual anterior cingulate cortex and anterior insula. Front Syst Neurosci. 2010;4: pii 33.
  • Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A (2015) Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. EMBO J 34:1056-1077.
  • Li M, Metzger CD, Li W, Safron A, van Tol M-J, Lord A, Krause AL, Borchardt V, Dou W, Genz A, Heinze H-J, He H, Walter M (2014) Dissociation of glutamate and cortical thickness is restricted to regions subserving trait but not state markers in major depressive disorder. J Affect Disord 169C:91-100.
  • Lord A, Horn D, Breakspear M, Walter M (2012) Changes in community structure of resting state functional connectivity in unipolar depression. PLoS One 7:e41282.
  • Metzger CD, Eckert U, Steiner J, Sartorius A, Buchmann JE, Stadler J, Tempelmann C, Speck O, Bogerts B, Abler B, Walter M. High field FMRI reveals thalamocortical integration of segregated cognitive and emotional processing in mediodorsal and intralaminar thalamic nuclei. Front Neuroanat. 2010 Nov 1;4:138.
  • Northoff G, Walter M, Schulte RF, Beck J, Dydak U, Henning A, Boeker H, Grimm S, Boesiger P. GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI. Nature Neuroscience 2007 Dec;10(12):1515-7.
  • Ranft K, Dobrowolny H, Krell D, Bielau H, Bogerts B, Bernstein HG. Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia. Psychol Med. 2010 Apr;40(4):557-67.
  • Scheidegger M, Walter M, Lehmann M, Metzger C, Grimm S, Boeker H, Boesiger P, Henning A, Seifritz E (2012) Ketamine Decreases Resting State Functional Network Connectivity in Healthy Subjects: Implications for Antidepressant Drug Action. PLoS One 7:e44799
  • Schreiber S, Bernstein HG, Fendrich R, Stauch R, Ketzler B, Dobrowolny H, Steiner J, Schreiber F, Bogerts B. Increased density of GAD65/67 immunoreactive neurons in the posterior subiculum and parahippocampal gyrus in treated patients with chronic schizophrenia. World J Biol Psychiatry. 2011 Jan 20.
  • Van Tol M-J, Li M, Metzger CD, Hailla N, Horn DI, Li W, Heinze HJ, Bogerts B, Steiner J, He H, Walter M (2013) Local cortical thinning links to resting-state disconnectivity in major depressive disorder. Psychol Med:1-13.
  • Walter M, Bermpohl F, Mouras H, Schiltz K, Tempelmann C, Rotte M, Heinze HJ, Bogerts B, Northoff G. Distinguishing specific sexual and general emotional effects in fMRI-subcortical and cortical arousal during erotic picture viewing. Neuroimage. 2008 May 1;40(4):1482-94.
  • Walter M, Henning A, Grimm S, Schulte RF, Beck J, Dydak U, Schnepf B, Boeker H, Boesiger P, Northoff G. The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression. Arch Gen Psychiatry. 2009 May;66(5):478-86.
  • Yang S, Yang Z, Fischer K, Zhong K, Stadler J, Godenschweger F, Steiner J, Heinze H-J, Bernstein H-G, Bogerts B, Mawrin C, Reutens DC, Speck O, Walter M (2013) Integration of ultra-high field MRI and histology for connectome based research of brain disorders. Front Neuroanat 7:31.
  • Yu C, Zhou Y, Liu Y, Jiang T, Dong H, Zhang Y, Walter M. Functional segregation of the human cingulate cortex is confirmed by functional connectivity based neuroanatomical parcellation. Neuroimage. 2011 Feb 14;54(4):2571-81.

Project A07

  • Bunzeck, N., Doeller, C.F., Dolan, R.J. & Duzel, E. Contextual interaction between novelty and reward processing within the mesolimbic system. Hum Brain Mapp (2011).
  • Bunzeck N, Doeller CF, Fuentemilla L, Dolan RJ, Duzel E. Reward motivation accelerates the onset of neural novelty signals in humans to 85 milliseconds. Curr Biol 19, 1294-300 (2009).
  • Chowdhury R, Guitart-Masip M, Bunzeck N, Dolan RJ, Duzel E (2012) Dopamine modulates episodic memory persistence in old age. J Neurosci 32:14193-14204.
  • Chowdhury R, Guitart-Masip M, Lambert C, Dolan RJ, Duzel E (2013) Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals. Neurobiol Aging 34:2261-2270.
  • Chowdhury R, Lambert C, Dolan RJ, Duzel E (2013) Parcellation of the human substantia nigra based on anatomical connectivity to the striatum. Neuroimage 81:191-198.
  • Duzel E, Bunzeck N, Guitart-Masip M, Duzel S NOvelty-related motivation of anticipation and exploration by dopamine (NOMAD): implications for healthy aging. Neurosci Biobehav Rev 34, 660-9 (2010).
  • Duzel E, Bunzeck N, Guitart-Masip M, Wittmann B, Schott BH, Tobler PN Functional imaging of the human dopaminergic midbrain. Trends Neurosci 32, 321-8 (2009).
  • Duzel E, Guitart-Masip M (2013) Not so uncertain at last: locus coeruleus and decision making. Neuron 79:9-11.
  • Guitart-Masip, M., Fuentemilla, L., Bach, D.R., Huys, Q.J., Dayan, P., Dolan, R.J. & Duzel, E. Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain. J Neurosci 31, 7867-75 (2011).
  • Guitart-Masip M, Bunzeck N, Stephan KE, Dolan, RJ, Duzel E. Contextual novelty changes reward representations in the striatum. J Neurosci 30, 1721-6 (2010).
  • M.B. Hoffmann, J. Stadler, M. Kanowski, O. Speck. Retinotopic mapping of the human visual cortex at a magnetic field strength of 7T. Clin Neurophysiol. 120(1):108-16 (2009)
  • Krebs RM, Schott BH, Duzel E. Personality traits are differentially associated with patterns of reward and novelty processing in the human substantia nigra/ventral tegmental area. Biol Psychiatry 65, 103-10 (2009).
  • Lisman J, Grace AA, Duzel E (2011) A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP. Trends Neurosci 34:536-547.
  • Maass A, Schutze H, Speck O, Yonelinas A, Tempelmann C, Heinze HJ, Berron D, Cardenas-Blanco A, Brodersen KH, Stephan KE, Duzel E (2014) Laminar activity in the hippocampus and entorhinal cortex related to novelty and episodic encoding. Nat Commun 5:5547.
  • Metzger CD, Eckert U, Steiner J, Sartorius A, Buchmann JE, Stadler J, Tempelmann C, O. Speck, Bogerts B, Abler B, Walter M. High field FMRI reveals thalamocortical integration of segregated cognitive and emotional processing in mediodorsal and intralaminar thalamic nuclei. Front Neuroanat. 2010 Nov 1;4:138
  • Speck O, Turner R (2013) Neurofunctional MRI at high magnetic fields. Radiologe 53:415-21. In MH, Posnansky O, Beall EB, Lowe MJ, Speck O (2015) Distortion correction in EPI using an extended PSF method with a reversed phase gradient approach. PLoS One 10(2):e0116320.
  • O. Speck, J. Stadler, M. Zaitsev, High-Resolution Single-Shot EPI at 7T. Magn. Reson. Mater Phy. 21(1-2): 73-86 (2008)
  • K. Zhong, T. Ernst, S. Buchthal, O. Speck, L. Anderson, L. Chang. Phase contrast imaging in neonates. Neuroimage. 2011 Jan 11. [Epub ahead of print]
  • T. Ball, T.P.K. Breckel, I. Mutschler, A. Aertsen, A. Schulze-Bonhage, J. Hennig, O. Speck. Variability of fMRI-Response Patterns at Different Spatial Observation Scales. HBM (in press)

Project A08

  • Barman A, Assmann A, Richter S, Soch J, Schütze H, Wüstenberg T, Deibele A, Klein M, Richter A, Behnisch G, Düzel E, Zenker M, Seidenbecher CI, Schott BH (2014). Genetic variation of the RasGRF1 regulatory region affects human hippocampus-dependent memory. Frontiers in Human Neuroscience 8:260.
  • Barman A, Richter S, Soch J, Deibele A, Richter A, Assmann A, Wüstenberg T, Walter H, Seidenbecher CI, Schott BH. Gender-specific modulation of neural mechanisms underlying social reward processing by Autism Quotient. Social, Cognitive and Affective Neuroscience, in press.
  • Dityatev A, Seidenbecher CI, Schachner M (2010). Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain. Trends Neurosci 33(11):503-12.
  • Düzel E, Bunzeck N, Guitart-Masip M, Wittmann B, Schott BH, Tobler PN (2009). Functional imaging of the human dopaminergic midbrain. Trends Neurosci 32(6):321-328.
  • Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A (2015). Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. EMBO J 34(8):1056-77.
  • Krebs RM, Schott BH, Düzel E (2009). Personality traits are differentially associated with reward and novelty processing in the human substantia nigra / ventral tegmental area. Biol Psychiatry 65(2):103-110.
  • Miró X, Meier S, Dreisow ML, Frank J, Strohmaier J, Breuer R, Schmäl C, Albayram Ö, Pardo-Olmedilla MT, Mühleisen TW, Degenhardt FA, Mattheisen M, Reinhard I, Bilkei-Gorzo A, Cichon S, Seidenbecher C, Rietschel M, Nöthen MM, Zimmer A (2012). Studies in humans and mice implicate neurocan in the etiology of mania. Am J Psychiatry 169(9):982-990.
  • Richter A, Richter S, Barman A, Soch J, Klein M, Assmann A, Behnisch G, Wüstenberg T, Seidenbecher CI, Schott BH (2013). Motivational salience and genetic variability of dopamine D2 receptor expression interact in the modulation of interference processing. Frontiers in Human Neuroscience 7:250.
  • Richter A, Guitart-Masip M, Barman A, Libeau C, Behnisch G, Czerney S, Schanze D, Assmann A, Klein M, Düzel E, Zenker M, Seidenbecher CI, Schott BH (2014). Valenced action/inhibition learning in humans is modulated by a genetic variant linked to dopamine D2 receptor expression. Frontiers in Systems Neuroscience 8:140.
  • Schicknick H, Schott BH, Budinger E, Smalla KH, Riedel A, Seidenbecher CI, Scheich H, Gundelfinger ED, Tischmeyer W (2008). Dopaminergic Modulation of Auditory Cortex-Dependent Memory Consolidation through mTOR. Cereb Cortex 18(11):2646-2658.
  • Schott BH, Assmann A, Schmierer P, Soch J, Garbusow M, Mohnke S, Pöhland L, Romanczuk-Seiferth N, Barman A, Wüstenberg T, Haddad L, Grimm O, Witt S, Richter S, Klein M, Schütze H, Mühleisen T, Cichon S, Rietschel M, Nöthen MM, Tost H, Gundelfinger ED, Düzel E, Heinz A, Meyer-Lindenberg A, Seidenbecher CI, Walter H (2014). Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding. Translational Psychiatry 4:e372.
  • Schott BH, Voss M, Wagner B, Wüstenberg T, Behr J. Fronto-limbic novelty processing in acute psychosis: disrupted relationship with memory performance and potential implications for delusions. Frontiers in Behavioral Neuroscience, in press.
  • Schott BH, Minuzzi L, Krebs RM, Elmenhorst D, Lang M, Winz O, Seidenbecher CI, Coenen H, Heinze HJ, Zilles K, Düzel, Bauer A (2008). Mesolimbic fMRI activations during reward anticipation correlate with reward-related ventral striatal dopamine release. J Neurosci 28(52):14311-14319.
  • Schott BH, Frischknecht R, Debska-Vielhaber G, John N, Behnisch G, Düzel E, Gundelfinger ED, Seidenbecher CI (2010). Membrane-bound catechol-O-methyl transferase in cortical neurons and glial cells is intracellularly oriented. Front Psychiatry 1:142.
  • Schott BH, Seidenbecher CI, Richter S, Wüstenberg T, Debska-Vielhaber G, Schubert H, Heinze HJ, Richardson-Klavehn A, Düzel E (2011a). Genetic variation of the serotonin 2a receptor affects hippocampal novelty processing in humans. PLoS ONE 6(1):e15984.
  • Schott BH, Niklas C, Kaufmann J, Bodammer N, Machts J, Schütze H, Düzel E (2011b). Fiber density between rhinal cortex and activated ventrolateral prefrontal regions predicts episodic memory performance in humans. Proc Natl Acad Sci USA, 108(13):5408-13.
  • Schott BH, Düzel E. The multiple roles of dopaminergic neurotransmission in episodic memory. In: E. Dere, A. Easton, L. Nadel and J.P. Huston (Eds.): Handbook of Episodic Memory, Vol. 18. Elsevier, Amsterdam, 2009.
  • Schott BH, Wüstenberg T, Wimber M, Fenker DB, Zierhut KC, Seidenbecher CI, Walter H, Düzel E, Richardson-Klavehn A (2013). The relationship between level of processing and hippocampal-cortical functional connectivity during episodic memory formation in humans. Human Brain Mapping 34(2):407-424.
  • Valenzuela JC, Heise C, Franken G, Singh J, Schweitzer B, Seidenbecher CI, Frischknecht R (2014). Hyaluronan-based extracellular matrix under conditions of homeostatic plasticity. Philos Trans R Soc Lond B Biol Sci 369(1654):20130606.
  • Wimber M, Schott BH, Wendler F, Seidenbecher CI, Behnisch G, Macharadze T, Bäuml KH, Richardson-Klavehn A. Prefrontal dopamine and the dynamic control of human long-term memory. Translat Psychiatry, in Druck.

Project A10E

  • Bergström ZM, Anderson MC, Buda M, Simons JS, Richardson-Klavehn A (2013). Intentional retrieval suppression can conceal guilty knowledge in ERP memory detection tests. Biological Psychology 94:1-11.
  • Guggenmos M, Thoma V, Cichy RM, Haynes JD, Sterzer P, Richardson-Klavehn A (2015). Non-holistic coding of objects in lateral occipital complex with and without attention. NeuroImage 107:356-363.
  • Guggenmos M, Thoma V, Haynes JD, Richardson-Klavehn A, Cichy RM, Sterzer P (2015). Spatial attention enhances object coding in local and distributed representations of the lateral occipital complex. NeuroImage 116:149-157.
  • Kizilirmak JM, Galvao Gomez da Silva J, Imamoglu F, Richardson-Klavehn A (2015). Generation and the subjective feeling of "aha!" are independently related to learning from insight. Psychological Research, in press.
  • Kizilirmak JM, Thürich H, Amos D, Richter A, Sweeney-Reed CM, Schott BH, Richardson-Klavehn A (in preparation). Thinking outside the box: Neural correlates of learning by insight.
  • Schott BH, Seidenbecher CI, Richter S, Wüstenberg T, Debska-Vielhaber G, Schubert H, Heinze HJ, Richardson-Klavehn A, Düzel E (2011). Genetic variation of the serotonin 2a receptor affects hippocampal novelty processing in humans. PLoS One 6:e15984.
  • Schott BH, Voss M, Wagner B, Wüstenberg T, Behr J (2015). Fronto-limbic novelty processing in acute psychosis: Disrupted relationship with memory performance and potential implications for delusions. Frontiers in Behavioral Neuroscience 9:144.
  • Schott BH, Wüstenberg T, Wimber M, Fenker DB, Zierhut KC, Seidenbecher CI, Walter H, Düzel E, Richardson-Klavehn A (2013). The relationship between level of processing and hippocampal-cortical functional connectivity during episodic memory formation in humans. Human Brain Mapping 34:407-424.
  • Soch J, Deserno L, Assmann A, Barman A, Walter H, Richardson-Klavehn A, Schott BH (in revision). Inhibitory control of information flow to the Default Mode Network during self-reference versus reference to others.
  • Staudigl T, Zaehle T, Voges J, Hanslmayr S, Esslinger C, Hinrichs H, Schmitt FC, Heinze HJ, Richardson-Klavehn A (2012). Memory signals from the thalamus: Early thalamocortical phase synchronization entrains gamma oscillations during long-term memory retrieval. Neuropsychologia 50:3519-3527.
  • Sweeney-Reed CM, Zaehle T, Voges J, Schmitt FC, Buentjen L, Kopitzki K, Esslinger C, Hinrichs H, Heinze HJ, Knight RT, Richardson-Klavehn A (2014). Corticothalamic phase synchrony and cross-frequency coupling predict human memory formation. Elife 3:e05352.
  • Sweeney-Reed CM, Zaehle T, Voges J, Schmitt FC, Buentjen L, Kopitzki K, Hinrichs H, Heinze HJ, Rugg MD, Knight RT, Richardson-Klavehn A (2015). Thalamic theta phase alignment predicts human memory formation and anterior thalamic cross-frequency coupling. Elife 4:e07578.
  • Thürich, H. (2015). Neuronale Korrelate von Einsichtslernen. Unpublished Master's thesis. Otto-von-Guericke-University, Magdeburg, Germany. A manuscript (Kizilirmak, Thürich, Schott, and Richardson-Klavehn) is currently in preparation.
  • Wheeler M, Schott BH, Richardson-Klavehn A, Wimber M (submitted for publication). Support for a role of the ventromedial prefrontal cortex in "online" memory consolidation via active retrieval.
  • Wimber M, Maaß, A, Staudigl T, Richardson-Klavehn A, Hanslmayr S. (2012). Rapid memory reactivation revealed by oscillatory entrainment. Current Biology 22:1482-1486.
  • Wimber M, Schott, BH, Wendler F, Seidenbecher CI, Behnisch G, Macharadze T, Bäuml KH, Richardson-Klavehn A (2011). Prefrontal dopamine and the dynamic control of human long-term memory. Translational Psychiatry 1:e15.
  • Zweynert S, Pade JP, Wüstenberg T, Sterzer P, Walter H, Seidenbecher CI, Richardson-Klavehn A, Düzel E, Schott BH (2011). Motivational salience modulates hippocampal repetition suppression and functional connectivity in humans. Frontiers in Human Neuroscience 5: e144.

Project A11E

  • Düzel E, Schütze H, Yonelinas AP, Heinze HJ. Functional phenotyping of successful aging in long-term memory: Preserved performance in the absence of neural compensation. Hippocampus. 2010 Jul 21. [Epub ahead of print]
  • Düzel S, Münte TF, Lindenberger U, Bunzeck N, Schütze H, Heinze HJ, Düzel E. Basal forebrain integrity and cognitive memory profile in healthy aging. Brain Res. 2010 Jan 13;1308:124-36. Epub 2009 Oct 23.
  • Fischer J, Schwiecker K, Bittner V, Heinze HJ, Voges J, Galazky I, Zaehle T: Modulation of Attentional Processing by Deep Brain Stimulation of the Pedunculopontine Nucleus Region in Patients With Parkinsonian Disorders. Neuropsychology. 2015 Feb 2. [Epub ahead of print]
  • Guitart-Masip M, Bunzeck N, Stephan KE, Dolan RJ, Düzel E. Contextual novelty changes reward representations in the striatum. J Neurosci. 2010 Feb 3;30(5):1721-6.
  • Heinze HJ, Heldmann M, Voges J, Hinrichs H, Marco-Pallares J, Hopf JM, Müller UJ, Galazky I, Sturm V, Bogerts B, Münte TF: Counteracting incentive sensitization in severe alcohol dependence using deep brain stimulation of the nucleus accumbens: clinical and basic science aspects. Front Hum Neurosci. 2009;3:22. Epub 2009 Sep 2.
  • Hinrichs H, Noesselt T, Heinze HJ Directed Information Flow—A Model Free Measure to Analyze Causal Interactions in Event Related EEG-MEG-Experiments. Human Brain Mapping, 2008, 29:193–206
  • Kluge C, Bauer M, Leff AP, Heinze HJ, Dolan RJ, Driver J: Plasticity of human auditory evoked fields induced by shock-conditioning and contingency reversal. Proc Natl Acad Sci U S A. (in press)
  • Kluge C, Marquardt F, Klug T, Tootell S, Fassnidge C, Richardson-Klavehn A, Schmitt FC, Kopitzki K, Zaehle T, Voges J, Hinrichs H, Kupsch A,m Galazky I: Pallidal stimulation modulates parkinsonian pedunculopontine nuclei. Annals of Clinical and Translational Neurology (under review)
  • Knight RT, Heinze HJ. The human brain: the final journey Front. Neurosci. doi:10.3389/ neuro.01.020.2008
  • Münte TF, Heldmann M, Hinrichs H, Marco-Pallares J, Krämer UM, Sturm V, Heinze HJ Contribution of subcortical structures to cognition assessed with invasive electrophysiology in humans Front. Neurosci. doi: 10.3389/neuro.01.006.2008
  • Noesselt T, Tyll S, Boehler CN, Budinger E, Heinze HJ, Driver J. Sound-induced enhancement of low-intensity vision: multisensory influences on human sensory-specific cortices and thalamic bodies relate to perceptual enhancement of visual detection sensitivity. J Neurosci. 2010 Oct 13;30(41):13609-23.
  • Schott BH, Minuzzi L, Krebs RM, Elmenhorst D, Lang M, Winz OH, Seidenbecher CI, Coenen HH, Heinze HJ, Zilles K, Düzel E, Bauer A. Mesolimbic functional magnetic resonance imaging activations during reward anticipation correlate with reward-related ventral striatal dopamine release. J Neurosci. 2008 Dec 24;28(52):14311-9.
  • Schott, BH, Niehaus L, Wittmann BC, Schütze H, Seidenbecher C, Heinze HJ, Düzel E. Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing Brain (2007) 130(9): 2412-2424.
  • Schott BH, Seidenbecher CI, Richter S, Wüstenberg T, Debska-Vielhaber G, Schubert H, Heinze HJ, Richardson-Klavehn A, Düzel E. Genetic variation of the serotonin 2a receptor affects hippocampal novelty processing in humans. PLoS One. 2011 Jan 18;6(1):e15984.
  • Stoppel CM, Boehler CN, Strumpf H, Heinze HJ, Hopf JM, Schoenfeld MA. Neural processing of reward magnitude under varying attentional demands. Brain Res. 2011 (in press).
  • Strumpf H, Noesselt T, Schoenfeld MA, Voges J, Panther P, Heinze HJ, Hopf JM: Deep brain stimulation of the pedunculopontine tegmental nucleus (PPN) influences visual contrast sensitivity in human observers. Plos One (under revision)
  • Tyll S, Zaehle T, Ball F, Schoenfeld MA, Galazky I, Voges J, Heinze HJ, Hopf JM, Noesselt T: The role of the pedunculopontine nucleus in multisensory integration. Brain Stimulation (under review)
  • Wimber M, Heinze HJ, Richardson-Klavehn A. Distinct frontoparietal networks set the stage for later perceptual identification priming and episodic recognition memory. J Neurosci. 2010 Oct 6;30(40):13272-80.

Project A12

  • Derix J, Yang S, Lüsebrink F, Fiederer LD, Schulze-Bonhage A, Aertsen A, Speck O, Ball T (2014) Visualization of the amygdalo-hippocampal border and its structural variability by 7T and 3T magnetic resonance imaging. Hum Brain Mapp 35: 4316-29.
  • Fischer AG, Endrass T, Kubisch C, Reuter M, Ullsperger M (2015). Serotonin reuptake inhibitors and serotonin transporter genotype modulate performance monitoring functions but not their EEG correlates. J Neurosci 35: 8181-8190.
  • Fischer AG, Endrass T, Goebel I, Reuter M, Montag C, Kubisch C, Ullsperger M (2015). Interactive effects of citalopram and serotonin transporter genotype on neural correlates of response inhibition and attentional orienting. Neuroimage 116: 59-67.
  • Fischer AG, Ullsperger M (2013) Real and fictive outcomes are processed differently but converge on a common adaptive mechanism. Neuron 79: 1243-55
  • In M-H, Posnansky O, Beall EB, Lowe MJ, Speck O (2015) Distortion Correction in EPI using an Extended PSF Method with a Reversed Phase Gradient Approach. PLoS one 10(2): e0116320
  • In M-H, Posnansky O, Speck O (2015) PSF Mapping-based Correction of Eddy-current-induced Distortions in Diffusion-weighted EPI. PLoS one, in press.
  • Jocham G, Klein TA, Ullsperger M (2014) Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonism. J Neurosci 34: 13151-13162.
  • Lüsebrink F, Wollrab A, Speck O (2012) Cortical thickness determination of the human brain using high resolution 3T and 7T MRI data. Neuroimage 70: 122-131.
  • Ullsperger M, Fischer AG, Nigbur R, Endrass T (2014) Neural mechanisms and temporal dynamics of performance monitoring. Trends Cogn Sci 18: 259-267.
  • Ullsperger M, Danielmeier C, Jocham G (2014) Neurophysiology of performance monitoring and adaptive behavior. Physiol Rev 94: 35-79.

Project A14N

  • Donamayor N, Marco-Pallares J, Heldmann M, Schoenfeld MA, Münte TF (2011). Temporal dynamics of reward processing revealed by magnetencephalography. Human Brain Mapping, 32, 2228-40.
  • Donohue SE, Todisco AE, Woldorff MG (2013). The rapid distraction of attentional resources toward the source of incongruent stimulus input during multisensory conflict. Journal of Cognitive Neuroscience, 25, 623-35.
  • Donohue SE, Roberts KC, Grent-'t-Jong T, Woldorff MG (2011). The cross-modal spread of attention reveals differential constraints for the temporal and spatial linking of visual and auditory stimulus events. Journal of Neuroscience, 31, 7982-90.
  • Donohue SE, Woldorff MG, Mitroff SR (2010). Video game players show more precise multisensory temporal processing abilities. Attention, Perception, & Psychophysics, 72, 1120-9.
  • Donohue, SE, Hopf, JM Bartsch, MV Schoenfeld, MA, Heinze, HJ, & Woldorff, MG (under revision). Electrophysiological correlates of object-based rewarded attentional capture.
  • Harris, JA, Barack, DL, McMahon, AR, Mitroff, SR, Woldorff, MG (2013). Object-category pro cessing, perceptual awareness, and the role of attention during motion-induced blindness in GR Mangun (Ed.), Cognitive Electrophysiology of Attention: Signals of the Mind (pp. 97-106). Davis, CA: Elsevier.
  • Harris, JA, McMahon, AR, Woldorff, MG (2013). Disruption of visual awareness during the at tentional blink is reflected by selective disruption of late-stage neural processing. Journal of Cognitive Neuroscience, 25, 1863-74.
  • Harris, JA, Ku, S, McMahon, AR, Woldorff, MG (2013). Neural processing stages during object- substitution masking and their relationship to perceptual awareness. Neuropsychologia, 51, 1907-1917.
  • Schoenfeld MA, Hopf JM, Merkel C, Heinze HJ, Hillyard SA (2014). Object-based attention involves the sequential activation of feature-specific cortical modules. Nature Neuroscience, 17, 619-26
  • Stoppel CM, Boehler CN, Strumpf H, Heinze HJ, Hopf JM, Schoenfeld MA (2011). Neural processing of reward under varying attentional demands. Brain Research, 1383, 218-29

Project A15N

  • Boehler CN, Hopf JM, Krebs RM, Stoppel CM, Schoenfeld MA, Heinze HJ, Noesselt T (2011a) Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward. J Neurosci 31: 4955-61.
  • Connolly AC, Guntupalli JS, Gors J, Hanke M, Halchenko YO, Wu YC, Abdi H, Haxby JV (2012) The representation of biological classes in the human brain. J Neurosci 32: 2608-2618.
  • Driver J & Noesselt T (2008). Multisensory interplay reveals crossmodal influences on 'sensory-specific' brain regions, neural responses, and judgements. Neuron 57:11-23.
  • Hanke M, Halchenko YO, Sederberg PB, Hanson SJ, Haxby JV, Pollmann S (2009) PyMVPA: A python toolbox for multivariate pattern analysis of fMRI data. Neuroinformatics 7:37-53.
  • Hanke M, Baumgartner FJ, Ibe P, Kaule FR, Pollmann S, Speck O, Zinke W, Stadler J (2014) A high-resolution 7-Tesla fMRI dataset from complex natural stimulation with an audio movie. Scientific Data 1. http://www.nature.com/articles/sdata20143
  • Haxby JV, Guntupalli JS, Connolly AC, Halchenko YA, Conroy BR, Gobbini MI, Hanke M, Peter J. Ramadge PJ (2011) A common, high-dimensional model of the representational space in human ventral temporal cortex. Neuron 72: 404–416
  • Noesselt T, Driver J, Heinze HJ, Dolan R (2005) Asymmetrical activation in the human brain during processing of fearful faces. Curr Biol 15:424-9.
  • Noesselt T, Tyll S, Boehler, CN, Heinze HJ, Budinger E, Driver J (2010) Sound-induced enhancement of low-intensity vision: Multisensory influences on human sensory-specific cortices and thalamic nuclei relate to perceptual enhancement of visual detection sensitivity. J Neurosci 30:13609-13623.
  • Ripolles P, Marco-Pallarés J, Hielscher U, Mestrés-Missé A, Tempelmann C,Heinze HJ, Rodriguez-Fornells A, Noesselt T (2014) The Role of Reward in Word Learning and its Implications for Language Acquisition. Curr Biol 24:2606-11.
  • Schoenfeld MA, Neuer G, Tempelmann C, Schussler K, Noesselt T, Hopf JM, Heinze HJ (2004) Functional magnetic resonance tomography correlates of taste perception in the human primary taste cortex. Neuroscience 127:347-53.

Project B01

  • Deliano M, Scheich H, Ohl FW (2009) Intracortical Microstimulation and its Role for Sensory Processing and Learning. J Neurosci 29: 15898-15909.
  • Hammer R, Brechmann A, Ohl FW, Weinshall D, Hochstein S (2010) Differential category learning processes: The neural basis of learning by comparison. Neuroimage 52: 699-709.
  • Happel MF, Deliano M, Handschuh J, Ohl FW (2014a) Dopamine-modulated recurrent corticoefferent feedback in primary sensory cortex promotes detection of behaviorally relevant stimuli. J Neurosci 34: 1234-1247.
  • Happel MF, Niekisch H, Castiblanco Rivera LL, Ohl FW, Deliano M, Frischknecht R (2014b) Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex. Proc Natl Acad Sci USA 111:2800-2805.
  • Happel MF, Jeschke M, Ohl FW (2010) Spectral integration in primary auditory cortex attributable to temporally precise convergence of thalamocortical and intracortical input. J. Neurosci 20: 11114-11127.
  • Ilango A, Shumake J, Wetzel W, Ohl FW (2014). Contribution of emotional and motivational neurocircuitry in cue signaled active avoidance learning. Front Behav Neurosci 8: 372.
  • Ilango A, Shumake J, Wetzel W, Scheich H, Ohl FW (2012) The role of dopamine in the context of aversive stimuli with particular reference to acoustically signaled avoidance learning. Front Neurosci 6: 132.
  • Ilango A, Wetzel W, Scheich H, Ohl FW (2010) The combination of appetitive and aversive reinforcers and the nature of their interaction during auditory learning. Neurosci. 166: 752-762.
  • Kähne T, Kolodziej A, Smalla K-H, Eisenschmidt E, Haus U-U, Weismantel R, Kropf S, Wetzel W, Ohl FW, Tischmeyer W, Naumann M, Gundelfinger A (2012) Synaptic proteom changes in mouse brain regions upon auditory discrimination learning. Proteomics 15-16: 2433-2444.
  • Kolodziej A, Lippert M, Angenstein F, Neubert J, Pethe A, Grosser OS, Amthauer H, Schroeder UH, Reymann KG, Scheich H, Ohl FW, Goldschmidt J (2014) SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice. NeuroImage 103C: 171-180.
  • Ohl FW (2014) Role of cortical neurodynamics for understanding the neural basis of motivated behavior - lessons from auditory category learning. Curr Opin Neurobiol 31C: 88-94.
  • Saldeitis K, Happel MF, Ohl FW, Scheich H, Budinger E (2014) Anatomy of the auditory thalamocortical system in the Mongolian gerbil: Nuclear origins and cortical field-, layer-, and frequency-specificities. J Comp Neurol 522: 2397-2430.
  • Scheich H, Brechmann A, Brosch M, Budinger E, Ohl FW, Selezneva E, Stark H, Tischmeyer W, Wetzel W (2011) Behavioral semantics of learning and crossmodal processing in auditory cortex: The semantic processor concept. Hear Res 271: 3-15.
  • Shumake J, Ilango A, Scheich H, Wetzel W, Ohl FW (2010) Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental area. J Neurosci 30: 5876-5883.
  • Takagaki K, Lippert MT, Dann B, Wanger T, Ohl FW (2008) Normalization of voltage-sensitive dye signal with functional activity measures. PLoS One 3: e4041.
  • Wanger T, Scheich H, Ohl FW, Goldschmidt J (2012) The use of thallium diethyldithiocarbamate (TlDDC) for mapping CNS potassium metabolism and neuronal activity: Tl(+) -redistribution, Tl(+) -kinetics and Tl(+) -equilibrium distribution. J Neurochem 122: 106-114.
  • Wanger T, Wetzel W, Scheich H, Ohl FW, Goldschmidt J (2014) Spatial patterns of neuronal activity in rat cerebral cortex during non-rapid eye movement sleep. Brain Struct Funct (in press).
  • Wetzel W, Ohl FW, Scheich H (2008) Global vs. local processing of frequency-modulated tones in gerbils: an animal model of lateralized auditory cortex functions in humans. Proc Natl Acad Sci USA 105: 6753-6758.

Project B02

  • Brosch M, Selezneva E, Scheich H (2005) Nonauditory events of a behavioral procedure activate auditory cortex of highly trained monkeys. J Neurosci 25:6797–6806.
  • Brosch M, Selezneva E, Scheich H (2011a) Formation of associations in auditory cortex by slow changes of tonic firing. Hear Res 271:66–73.
  • Brosch M, Selezneva E, Scheich H (2011b) Representation of Reward Feedback in Primate auditory Cortex. Front. Syst. Neurosci. 5:5. doi: 10.3389/fnsys.2011.00005.
  • Brosch, M, Budinger, E, Scheich, H (2013) Different synchronization rules in primary and nonprimary auditory cortex of monkeys. J Cogn Neurosci, 25, 1517–1526.
  • Brosch, M (2013) Associations and Rewards in Auditory Cortex. Encyclopedia of Computational Neuroscience. In: Jaeger D, Jung R (eds) Encyclopedia of Computational Neuroscience: SpringerReference (www.springerreference.com). Springer-Verlag Berlin Heidelberg.
  • Brosch, M, Selezneva, E, Scheich, H (2015) Neuronal activity in primate auditory cortex during the performance of audiovisual tasks. Eur J Neurosci, 41, 603–614.
  • Dürschmid, S, Zaehle, T, Hinrichs, H, Heinze, HJ, Voges, J, Garrido, M, Dolan, R, Knight, RT (2015) Sensory deviancy detection measured directly within human nucleus accumbens. Cerebr Cortex [Epub ahead of print].
  • Herrmann, T, Mallow, J, Plaumann, M, Luchtmann, M, Stadler, J, Mylius, J, Brosch, M, Bernarding, J (2015) The travelling-wave primate system: a new solution for magnetic resonance imaging of macaque monkeys at 7 Tesla ultra-high field. PLoS One, 10, e0129371. doi: 10.1371/journal.pone.0129371.
  • Huang, Y, Mylius, J, Scheich, H, Brosch, M (2014) Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys. Brain Struct Funct, doi: 10.1007/s00429-014-0950-2.
  • Ilango A, Wetzel W, Scheich H, Ohl FW (2010) The combination of appetitive and aversive reinforcers and the nature of their interaction during auditory learning. Neurosci 166:752-62.
  • Lovell, JM, Mylius, J, Scheich, H, Brosch, M (2015) Stimulation of the dopaminergic ventral midbrain as a behavioural reward in instrumentally conditioned monkeys. Brain Stimulation, doi: 10.1016/j.brs.2015.04.007.
  • Mylius, J, Happel, MF, Gorkin, AG, Huang, Y, Scheich, H, Brosch, M (2014) Fast transmission from the dopaminergic ventral midbrain to the sensory cortex of awake primates. Brain Struct Funct, doi:10.1007/s00429-014-0855-0.
  • Rahne T, Deike S, Selezneva E, Brosch M, König R, Scheich H, Böckmann M, Brechmann A (2008) A multilevel approach towards neuronal mechanisms of streaming. Brain Res 1220: 118-131.
  • Scheich H, Brechmann A, Brosch M, Budinger E, Ohl FW, Selezneva E, Stark H, Tischmeyer W, Wetzel W (2011) Behavioral semantics of learning and crossmodal processing in auditory cortex: The semantic processor concept. Hear Res 271: 3-15.
  • Scheich, H. and Brosch, M. (2013) Task-related activation of the auditory cortex. in: Springer Handbook of Auditory Research, Volume: 'Neural Correlates of Auditory Cognition', Cohen, Yale E.; Popper, Arthur N.; Fay, Richard R. (Eds.).
  • Scheich H, Ohl FW (2010) A Semantic Concept of Auditory Cortex Function and Learning. In J Winer, & C. E. Schreiner (Eds.) The Auditory Cortex (pp 369-386). New York: Springer.
  • Schicknick H, Schott BH, Budinger E, Smalla KH, Riedel A, Seidenbecher CI, Scheich H, Gundelfinger ED, Tischmeyer W (2008) Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex 18:2646-58
  • Selezneva E, Scheich H, Brosch M (2006) Dual time scales for categorical decision making in auditory cortex. Curr Biol 16: 2428-2433.
  • Shumake J, Ilango A, Scheich H, Wetzel W, Ohl FW (2010) Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental area. J Neurosci 30:5876-83.
  • Stark H, Scheich H. (1997) Dopaminergic and serotonergic neurotransmission systems are differentially involved in auditory cortex learning: a long-term microdialysis study of metabolites. J Neurochem 68:691-697.
  • Stenner, MP, Litvak, V, Rutledge, RB, Zaehle, T, Schmitt, FC, Voges, J, Heinze, HJ, Dolan, RJ (2015a) Cortical drive of low-frequency oscillations in the human nucleus accumbens during action selection. J Neurophysiol, doi: 10.1152/jn.00988.201.
  • Stenner, MP, Rutledge, RB, Zaehle, T, Schmitt, FC, Kopitki, K, Kowski, AB, Voges, J, Heinze, HJ, Dolan, RJ (2015b) No unified reward prediction error in local field potentials from the human nucleus accumbens: evidence from epilepsy patients. J Neurophysiol, doi: 10.1152/jn.00260.2015.
  • Sweeney-Reed, CM, Zaehle, T, Voges, J, Schmitt, FC., Buentjen, L, Kopitzki, K, Esslinger, C, Hinrichs, H, Heinze, HJ, Knight, RT, Richardson-Klavehn, A (2015) Thalamic theta phase alignment predicts human memory formation and anterior thalamic cross-frequency coupling. /eLife/, /10.7554/eL/(May). doi: 10.7554/eLife.07578.001
  • Sweeney-Reed, CM, Zaehle, T, Voges, J, Schmitt, FC., Buentjen, L, Kopitzki, K, Hinrichs, H, Heinze, HJ., Rugg, MD, Knight, RT, Richardson-Klavehn, A (2014) Corticothalamic phase synchrony and cross-frequency coupling predict human memory formation. /eLife/, /3:e05352/. doi:10.7554/eLife.05352

Project B05

  • Albrecht A, Bergado-Acosta JR, Pape HC, Stork O (2010) Role of the neural cell adhesion molecule (NCAM) in amygdalo-hippocampal interactions and salience determination of contextual fear memory. Int J Neuropsychopharmacol 13:661-674
  • Albrecht A, Çalışkan G, Oitzl MS, Heinemann U, Stork O (2013) Long-lasting increase of corticosterone after fear memory reactivation: anxiolytic effects and network activity modulation in the ventral hippocampus. Neuropsychopharmacology 38: 386-394.
  • Albrecht A, Thiere M, Bergado-Acosta JR, Poranzke J, Müller B, Stork O (2014) Circadian modulation of anxiety: a role for somatostatin in the amygdala. PLoS One 8: e84668.
  • Bergado-Acosta JR, Sangha S, Narayanan RT, Obata K, Pape HC, Stork O (2008) Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memory. Learn Mem 15:163-171.
  • Bergado-Acosta JR, Müller I, Richter-Levin G, Stork O (2014) The GABA-synthetic enzyme GAD65 controls circadian activation of conditioned fear pathways. Behav Brain Res 260: 92-100.
  • Çalışkan G, AlbrechtA, Hollnagel JO, Richter-Levin G, Heinemann U, Stork O (2015a) Long-term changes in the CA3 associative network of fear-conditioned mice. Stress 30: 1-10.
  • Hadad-Ophir O, Albrecht A, Stork O, Richter-Levin G (2014) Amygdala activation and GABAergic gene expression in hippocampal sub-regions at the interplay of stress and spatial learning. Front Behav Neurosci 8: 3.
  • Janitzky K, Linke R, Yilmazer-Hanke DM, Grecksch G, Schwegler H (2007) Disrupted visceral feedback reduces locomotor activity and influences background contextual fear conditioning in C57BL/6JOla Hsd mice. Behav Brain Res 182: 109-118.
  • Janitzky K, Stork O, Lux A, Yanagawa Y, Schwegler H, Linke R (2009) Behavioral effects and pattern of brain c-fos mRNA induced by 2,5-dihydro-2,4,5-trimethylthiazoline, a component of fox feces odor in GAD67-GFP knock-in C57BL/6 mice. Behav Brain Res 202: 218-224.
  • Janitzky K, Schwegler H, Kröber A, Roskoden T, Yanagawa Y, Linke R (2011) Species-relevant life-threatening inescapable stress differently influences memory consolidation and retrieval of mice in a spatial radial arm maze. Behav. Brain Res 219: 142-148.
  • Kluge C, Stoppel C, Szinyei C, Stork O, Pape HC (2008) Role of the somatostatin system in contextual fear memory and hippocampal synaptic plasticity. Learn Mem 15:252-260.
  • Li L, Sase A, Patil S, Sunyer B, Höger H, Smalla KH, Stork O, Lubec G (2013) Distinct set of kinases induced after retrieval of spatial memory discriminate memory modulation processes in the mouse hippocampus. Hippocampus 23: 672-683. [joint last authorship]
  • Lubec G, Li L, Sunyer B, Patil SS, Höger H, Smalla K-H, Pollak A, Stork O (2011) Hippocampal protein kinase and phosphatase levels in CD1 mice trained and untrained in the Morris Water Maze. Neurobiol Learn Mem, submitted
  • Meis S, Bergado-Acosta JR, Yanagawa Y, Obata K, Stork O, Munsch T (2009) Identification of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus. PLoSOne 3:e2695.
  • Meis S, Stork O, Munsch T (2011) Neuropeptide S-mediated facilitation of synaptic transmission enforces subthreshold theta oscillations within the lateral amygdala. PLoSOne 6:e18020.
  • Müller M, Faber-Zuschratter H, Yanagawa Y, Stork O, Schwegler H, Linke R (2011) Synaptology of ventral CA1 and subiculum projections to the basomedial nucleus of the amygdala in the mouse: relation to GABAergic interneurons. Brain Struct Funct, Epub ahead of print.
  • Müller M, Faber-Zuschratter H, Yanagawa Y, Stork O, Schwegler H, Linke R (2012) Synaptology of ventral CA1 and subiculum projections to the basomedial nucleus of the amygdala in the mouse, relation to GABAergic interneurons. Brain Struct Funct 217: 5-17.
  • Müller I, Obata K, Richter-Levin G, Stork O (2014) GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathology. Front Behav Neurosci 8: 265.
  • Nullmeier S, Panther P, Dobrowolny H, Frotscher M, Zhao S, Schwegler H, Wolf R (2011) Immunhistochemical studies in heterozygous reeler mice, a potential animal model f schizophrenia. Eur. J. Neurosci 33: 689-698
  • Sandhu KV, Lang D, Müller B, Nullmeier S, Yanagawa Y, Schwegler H, Stork O (2013) Glutamic acid decarboxylase 67 haplodeficiency impairs social behavior in mice. Genes Brain Behav 13: 439-450.
  • Sangha S, Narayanan RT, Bergado-Acosta JR, Stork O, Seidenbecher T, Pape HC (2009) Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory. J Neurosci 29: 15713-15720.
  • Santos M, D'Amico D, Spadoni O, Amador-Arjona A, Stork O, Dierssen M (2013) Hippocampal hyperexcitability underlies enhanced fear memories in TgNTRK3, a panic disorder mouse model. J Neurosci 33: 15259-15271.

Project B06

  • Abidin I, Eysel UT, Lessmann V, Mittmann T (2008) Impaired GABAergic inhibition in the visual cortex of BDNF heterozygous knock out mice. Journal of Physiology 586.7: 1885-1901.
  • Edelmann E, Cepeda-Prado E, Franck M, Lichtenecker P, Brigadski T, Lessmann V (2015) Theta burst firing recruits BDNF release and signaling in postsynaptic CA1 neurons in Spike-timing-dependent LTP. Neuron 86: 1041-1054.
  • Edelmann E, Lessmann V (2013) Dopamine regulates intrinsic excitability thereby gating successful induction of spike timing-dependent plasticity in CA1 of the hippocampus. Front Neurosci 7:25.
  • Edelmann E, Lessmann V, Brigadski T (2014) Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity. Neuropharmacology 76 Pt C:610-27.
  • Endres T, Lessmann V (2012) Age-dependent deficits in fear learning in heterozygous BDNF knock-out mice. Learn Mem 19:561-570.
  • Gottmann K, Mittmann T, Lessmann V (2009) BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses. Experimental Brain Research 199:203–234
  • Kolarow R, Brigadski T, Lessmann V (2007) Postsynaptic secretion of BDNF and NT-3 from hippocampal neurons depends on calcium calmodulin kinase II signaling and proceeds via delayed fusion pore opening. Journal of Neuroscience 27:10350-10364.
  • Kuczewski N, Porcher C, Ferrand N, Fiorentino H, Pellegrino C, Kolarow R, Lessmann V, Medina I, Gaiarsa JL (2008) Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity. Journal of Neuroscience 28:7013-7023.
  • Kuczewski N, Porcher C, Lessmann V, Medina I, Gaiarsa JL (2009) Activity-dependent dendritic release of BDNF and biological consequences. Molecular Neurobiology 39:37-49.
  • Laudes T, Meis S, Munsch T, Lessmann V (2012) Impaired transmission at corticothalamic excitatory inputs and intrathalamic GABAergic synapses in the ventrobasal thalamus of heterozygous BDNF knockout mice. Neuroscience 222:215-27.
  • Lessmann V, Brigadski T (2009) Mechanisms, locations, and kinetics of synaptic BDNF secretion: an update. Neuroscience Res 65:11-22.
  • Lessmann V, Stroh-Kaffei S, Steinbrecher V, Edelmann E, Brigadski T, Kilb W, Luhmann HJ. The expression mechanism of the residual LTP in the CA1 region of BDNF k.o mice is insensitive to NO synthase inhibition Brain Research 1391: 14-23 (2011).
  • Meis S, Stork O, Munsch T (2011) Neuropeptide S-mediated facilitation of synaptic transmission enforces subthreshold theta oscillations within the lateral amygdala. PLoS One 6: e18020. colab. B05
  • Meis S, Endres T, Lessmann V (2012) Postsynaptic BDNF signalling regulates long-term potentiation at thalamo-amygdala afferents. J Physiol 590:193-208.
  • Psotta L, Lessmann V, Endres T (2013) Impaired fear extinction learning in adult heterozygous BDNF knock-out mice. Neurobiol Learn Mem 103:34-38.
  • Schildt S, Endres T, Lessmann V, Edelmann E (2013) Acute and chronic interference with BDNF/TrkB-signaling impair LTP selectively at mossy fiber synapses in the CA3 region of mouse hippocampus. Neuropharmacology 71:247-254.
  • Schulz-Klaus B, Lessmann V, Endres T (2013) BDNF-dependent consolidation of fear memories in the perirhinal cortex. Front Behav Neurosci 7:205.
  • Xia X, Lessmann V, Martin TF (2009) Imaging of evoked dense-core-vesicle exocytosis in hippocampal neurons reveals long latencies and kiss-and-run fusion events. J Cell Sci 122:75-82.

Project B08

  • Behnisch T, Ping An YX, Bethge P, Parvez S, Jin Y, Ying C, Karpova A, Frey JU, Mikhaylova M, Kreutz MR. (2011) Nuclear translocation of Jacob in hippocampal neurons after stimuli inducing long-term potentiation but not long-term depression. PLoS One 6(2):e17276.
  • Bera S, Kreutz MR (2014) When synaptic proteins meet the genome: transcriptional regulation in cell death and plasticity by the synapto-nuclear messenger Jacob. Neuropsychopharmacology 9: 245-246.
  • Dieterich DC, Karpova A, Mikhaylova M, Zdobnova I, König I, Landwehr M, Kreutz M, Smalla KH, Richter K, Landgraf P, Reissner C, Böckers TM, Zuschratter W, Spilker C, Seidenbecher CI, Garner CC, Gundelfinger ED, Kreutz MR (2008) Caldendrin – Jacob: A Protein Liaison that Couples NMDA Receptor Signalling to the Nucleus. PLoS Biology 6:e34.
  • Gomes GM, Dalmolin GD, Bär J, Karpova A, Mello CF, Kreutz MR, Rubin MA (2014) Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors. PLoS One 9: e99184.
  • Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, Boeckers TM. Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO Journal 30(3):569-81, 2011.
  • Grabrucker S, Jannetti L, Eckert M, Gaub S, Chhabra R, Pfaender S, Mangus K, Reddy PP, Rankovic V, Schmeisser MJ, Kreutz MR, Ehret G, Boeckers TM, Grabrucker AM (2014) Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders. Brain 137:137-152.
  • Jordan BA, Kreutz MR (2009) Nucleocytoplasmic protein shuttling: The direct route in synapse-to-nucleus signaling. Trends in Neurosci. 32: 392-401.
  • Karpova A, Mikhaylova M, Bera S, Bär J, Reddy PP, Behnisch T, Rankovic V, Spilker C, Bethge P, Sahin J, Kaushik R, Zuschratter W, Kähne T, Naumann M, Gundelfinger ED, Kreutz MR (2013) Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptor signals to the nucleus. Cell 152: 1119–1133. *Research highlight in Nature Reviews Neuroscience. *Hot Topic Neuropsychopharmacology. Collaboration with B09 and Z-project.
  • Kaushik R, Grochowska KM, Butnaru I, Kreutz MR (2014) Protein trafficking from synapse to nucleus in control of activity-dependent gene expression. Neuroscience 280: 340-350.
  • Kindler S, Dieterich DC, Schütt J, Sahin J, Karpova A, Mikhaylova M, Schob C, Gundelfinger ED, Kreienkamp HJ, Kreutz MR (2009) Dendritic mRNA targeting of Jacob and NMDA-induced nuclear translocation pool after Calpain-mediated proteolysis. J Biol Chem. 284: 25431-25440.
  • Macharadze T, Pielot R, Wanger T, Scheich H, Gundelfinger ED, Budinger E, Goldschmidt J, Kreutz MR (2012) Altered neuronal activity patterns in the visual cortex of the adult rat after partial optic nerve crush--a single-cell resolution metabolic mapping study. Cereb Cortex 22: 1824-1833. Collaboration with B02, B09, B13.
  • Mikhaylova M, Reddy PP, Munsch T, Landgraf P, Suman SK, Smalla KH, Gundelfinger ED, Sharma Y, Kreutz MR. Calneurons provide a Calcium-threshold for trans-Golgi network to plasma membrane trafficking. Proc. Natl. Acad. Sci. 106:9093-9098, 2009.
  • Mikhaylova M, Karpova A, Bär J, Bethge P, YuanXiang P, Chen Y, Zuschratter W, Behnisch T, Kreutz MR (2014) Cellular distribution of the NMDA-receptor activated synapto-nuclear messenger Jacob in the rat brain. Brain Struct Funct 219: 843-860.
  • Panayotis N, Karpova A, Kreutz MR, Fainzilber M (2015) Macromolecular transport in synapse to nucleus communication. Trends Neurosci 38: 108-116.
  • Rönicke R, Mikhaylova M, Rönicke S, Meinhardt J, Schröder UH, Fändrich M, Reiser G, Kreutz MR, Reymann KG (2011) Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiol. of Aging 2010 Feb 2. [Epub ahead of print]
  • Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck St, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmitz D, Kreutz MR, Bourgeron T, Gundelfinger ED, Boeckers TM (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486: 256-260. Collaboration with B09.
  • Smalla KH, Mikhaylova M, Sahin J, Bernstein HG, Bogerts B, Schmitt A, van der Schors R, Smit AB, Li KW, Gundelfinger ED, Kreutz MR (2008) A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that Prohibitin is involved in the synaptic pathology of schizophrenia. Mol. Psychiatry 13: 878-896.
  • Yuanxiang P, Bera S, Karpova A, Kreutz MR, Mikhaylova M (2014) Isolation of CA1 nuclear enriched fractions from hippocampal slices to study activity-dependent nuclear import of synapto-nuclear messenger proteins. J Vis Exp. 90: e51310.

Project B09

  • Davydova D, Marini C, King C, Klueva J, Bischof F, Romorini S, Montenegro-Venegas C, Heine M, Schneider R, Schroder MS, Altrock WD, Henneberger C, Rusakov DA, Gundelfinger ED, Fejtova A (2014) Bassoon Specifically Controls Presynaptic P/Q-type Ca2+ Channels via RIM-Binding Protein. Neuron 82:181-194.
  • Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc Natl Acad Sci U S A 103:9482-9487.
  • Dieterich DC, Hodas JJ, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, Schuman EM (2010) In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nat Neurosci 13:897-905.
  • Dieterich DC, Karpova A, Mikhaylova M, Zdobnova I, Konig I, Landwehr M, Kreutz M, Smalla KH, Richter K, Landgraf P, Reissner C, Boeckers TM, Zuschratter W, Spilker C, Seidenbecher CI, Garner CC, Gundelfinger ED, Kreutz MR (2008) Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. PLoS Biol 6:e34.
  • Erdmann I, Marter K, Kobler O, Niehues S, Abele J, Müller A, Bussmann J, Storkebaum E, Ziv T, Thomas U, Dieterich DC (2015) Cell-selective labeling of proteomes in Drosophila melanogaster. Nat Comm DOI: 10.1038/ncomms8521
  • Fejtova A, Davydova D, Bischof F, Lazarevic V, Altrock WD, Romorini S, Schone C, Zuschratter W, Kreutz MR, Garner CC, Ziv NE, Gundelfinger ED (2009) Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. J Cell Biol 185:341-355.
  • Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, Boeckers TM (2011) Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO J 30:569-581.
  • Hallermann S, Fejtova A, Schmidt H, Weyhersmuller A, Silver RA, Gundelfinger ED, Eilers J (2010) Bassoon speeds vesicle reloading at a central excitatory synapse. Neuron 68:710-723.
  • Ivanova D, Dirks A, Montenegro-Venegas C, Schöne C, Altrock WD, Marini C, Frischknecht R, Schanze D, Zenker M, Gundelfinger ED, Fejtova A (2015) Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. EMBO J 34:1056-1077.
  • Jüch M, Smalla KH, Kahne T, Lubec G, Tischmeyer W, Gundelfinger ED, Engelmann M (2009) Congenital lack of nNOS impairs long-term social recognition memory and alters the olfactory bulb proteome. Neurobiol Learn Mem 92:469-484.
  • Kähne T, Kolodziej A, Smalla KH, Eisenschmidt E, Haus UU, Weismantel R, Kropf S, Wetzel W, Ohl FW, Tischmeyer W, Naumann M, Gundelfinger ED (2012) Synaptic proteome changes in mouse brain regions upon auditory discrimination learning. Proteomics 12:2433-2444.
  • Karpova A, Mikhaylova M, Bera S, Bar J, Reddy PP, Behnisch T, Rankovic V, Spilker C, Bethge P, Sahin J, Kaushik R, Zuschratter W, Kähne T, Naumann M, Gundelfinger ED, Kreutz MR (2013) Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus. Cell 152:1119-1133. (cooperation with project B08)
  • Kindler S, Dieterich DC, Schutt J, Sahin J, Karpova A, Mikhaylova M, Schob C, Gundelfinger ED, Kreienkamp HJ, Kreutz MR (2009) Dendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysis. J Biol Chem 284:25431-25440.
  • Lazarevic V, Schöne C, Heine M, Gundelfinger ED, Fejtova A (2011) Extensive remodeling of the pre-synaptic cytomatrix upon homeostatic adaptation to network activity silencing. J Neurosci, in press
  • Ngo JT, Champion JA, Mahdavi A, Tanrikulu IC, Beatty KE, Connor RE, Yoo TH, Dieterich DC, Schuman EM, Tirrell DA (2009) Cell-selective metabolic labeling of proteins. Nat Chem Biol 5:715-717.
  • Reichenbach N, Herrmann U, Kähne T, Schicknick H, Pielot R, Naumann M, Dieterich DC, Gundelfinger ED, Smalla KH, Tischmeyer W (2015) Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain. Proteome Sci 13:13.
  • Rosenberg T, Gal-Ben-Ari S, Dieterich DC, Kreutz MR, Ziv NE, Gundelfinger ED, Rosenblum K (2014) The roles of protein expression in synaptic plasticity and memory consolidation. Front Mol Neurosci 7:86. (review)
  • Scheich H, Brechmann A, Brosch M, Budinger E, Ohl FW, Selezneva E, Stark H, Tischmeyer W, Wetzel W (2011) Behavioral semantics of learning and crossmodal processing in auditory cortex: the semantic processor concept. Hear Res 271:3-15.
  • Schicknick H, Schott BH, Budinger E, Smalla KH, Riedel A, Seidenbecher CI, Scheich H, Gundelfinger ED, Tischmeyer W (2008) Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex 18:2646-2658.
  • Schicknick H, Reichenbach N, Smalla KH, Scheich H, Gundelfinger ED, Tischmeyer W (2012) Dopamine modulates memory consolidation of discrimination learning in the auditory cortex. Eur J Neurosci 35:763-774.
  • Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, tom Dieck S, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmitz D, Kreutz MR, Bourgeron T, Gundelfinger ED, Böckers TM (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486:256-260. (cooperation with project B08 and others)
  • Schott BH, Assmann A, Schmierer P, Soch J, Erk S, Garbusow M, Mohnke S, Pohland L, Romanczuk-Seiferth N, Barman A, Wustenberg T, Haddad L, Grimm O, Witt S, Richter S, Klein M, Schutze H, Muhleisen TW, Cichon S, Rietschel M, Noethen MM, Tost H, Gundelfinger ED, Duzel E, Heinz A, Meyer-Lindenberg A, Seidenbecher CI, Walter H (2014) Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding. Transl Psychiatry 4:e372. (cooperation with project A08)

Project B11

  • Andreatta M, Fendt M, Mühlberger A, Wieser MJ, Imobersteg S, Yarali A, Gerber B, Pauli P (2012) Onset and offset of aversive events establish distinct memories requiring fear and reward networks. Learn Mem 19:518-526.
  • Diegelmann S, Klagges B, Michels B, Schleyer M, Gerber B (2013a) Maggot learning and Synapsin function. J Exp Biol 216:939-951.
  • Diegelmann S, Preuschoff S, Appel M, Niewalda T, Gerber B, Yarali A (2013b) Memory decay and susceptibility to amnesia dissociate punishment - from relief-learning. Biol Lett 9:20121171.
  • Gerber B, Tanimoto H & Heisenberg M (2004) An engram found? Evaluating the evidence from fruit flies. Current Opinion in Neurobiology 14, 737-44.
  • *Gerber B, Yarali A, Diegelmann S, Wotjak CT, Pauli P, Fendt M (2014) Pain-relief learning in flies, rats, and man: basic research and applied perspectives. Learn Mem 21:232-252.
  • Knapek S, Gerber B, Tanimoto H (2010) Synapsin is selectively required for anesthesia-sensitive memory. Learning & Memory 17, 76-79.
  • Michels B, Diegelmann S, Tanimoto H, Schwenkert I, Buchner E & Gerber B (2005) A role of Synapsin for associative learning: The Drosophila larva as a study case. Learning & Memory 12, 224-31.
  • Michels B, Chen Y-c Saumweber T, Mishra D, Tanimoto H, Schmid B, Engmann O, Gerber B (2011) Cellular site and molecular mode of Synapsin action in associative learning. Learning & Memory 18, 332-344.
  • Mishra D, Chen YC, Yarali A, Oguz T, Gerber B (2013) Olfactory memories are intensity specific in larval Drosophila. J Exp Biol 216:1552-1560.
  • *Niewalda T, Michels B, Jungnickel R, Diegelmann S, Kleber J, Kähne T, Gerber B (2015) Synapsin determines memory strength after punishment- and relief-learning. J Neurosci 35:7487-7502.
  • Sadanandappa MK, Blanco Redondo B, Michels B, Rodrigues V, Gerber B, VijayRaghavan K, Buchner E, Ramaswami M (2013) Synapsin function in GABA-ergic interneurons is required for short-term olfactory habituation. J Neurosci 33:16576-16585.
  • Saumweber T, Cano C, Klessen J, Eichler K, Fendt M, Gerber B (2014) Immediate and punitive impact of mechanosensory disturbance on olfactory behaviour of larval Drosophila. Biol Open 3:1005-1010.
  • Schleyer M, Miura D, Tanimura T, Gerber B (2015a) Learning the specific quality of taste reinforcement in larval Drosophila. eLife 4:e04711.
  • Schleyer M, Reid SF, Pamir E, Saumweber T, Paisios E, Davies A, Gerber B, Louis M (2015b) The impact of odor-reward memory on chemotaxis in larval Drosophila. Learn Mem 22:267-277.
  • Tanimoto H, Heisenberg M & Gerber B (2004) Event-timing turns punishment to reward. Nature 430, 983.
  • Yarali A, Gerber B (2010) A neurogenetic dissociation between punishment-, reward- and relief-learning in Drosophila. Frontiers in Behavioral Neuroscience 23, 189.
  • Yarali A, Krischke M, Michels M, Saumweber T, Mueller MJ & Gerber B (2009) Genetic distortion of the balance between punishment and relief learning in Drosophila. J Neurogenetics 23, 235-47.
  • Yarali A, Niewalda T, Chen Y-c, Tanimoto H, Duerrnagel S & Gerber B (2008) Pain-relief learning in fruit flies. Animal Behaviour 76, 1173-85.

*Featured as cover

Project B13N

  • Andreatta M, Fendt M, Mühlberger A, Wieser MJ, Imobersteg S, Yarali A, Gerber B & Pauli P (2012) Onset and offset of aversive events establish distinct memories requiring fear- and reward networks. Learn Mem 19: 518-526.
  • *Apostolova I, Wunder A, Dirnagl U, Michel R, Stemmer N, Lukas M, Derlin T, Gregor-Mamoudou B, Goldschmidt J, Brenner W, Buchert R (2013) Brain perfusion SPECT in the mouse: normal pattern according to gender and age. Neuroimage 63:1807-1817.
  • Daldrup T, Remmes J, Lesting J, Gaburro S, Fendt M, Meuth P, Kloke V, Pape HC & Seidenbecher T (2015) Expression of freezing and fear-potentiated startle during sustained fear in mice. Gene Brain Behav 14: 281-291.
  • Fendt M & Koch M (2013) Translational value of startle modulations. Cell Tiss Res 354: 287-295.
  • Gerber B, Yarali A, Diegelmann S, Wotjak CT, Pauli P & Fendt M (2014) Pain-relief learning in flies, rats, and man: Basic research and applied perspectives. Learn Mem 21: 232-252.
  • Kahl E & Fendt M (2014) Injections of the somatostatin receptor type 2 agonist L-054,264 into the amygdala block expression but not acquisition of conditioned fear in rats. Behav Brain Res 265: 49-52.
  • Kahl E & Fendt M (2015) Metabotropic glutamate receptors 7 in the nucleus accumbens are involved in relief learning in rats. Curr Neuropharmacol: in press.
  • *Kolodziej A, Lippert M, Angenstein F, Neubert J, Pethe A, Grosser OS, Amthauer H, Schroeder UH, Reymann KG, Scheich H, Ohl FW, Goldschmidt J (2014) SPECT-imaging of activity-dependent changes in regional cerebral blood flow induced by electrical and optogenetic self-stimulation in mice. Neuroimage 103:171-80.
  • Mohammadi M, Bergado-Acosta JR & Fendt M (2014) Relief learning is distinguished from safety learning by the requirement of the nucleus accumbens. Behav Brain Res 272: 40-45.
  • Mohammadi M & Fendt M (2015) Relief learning is dependent on NMDA receptor activation in the nucleus accumbens. Br J Pharmacol 172: 2419-2426.
  • Saumweber T, Cano C, Klessen J, Eichler K, Fendt M & Gerber B (2014) Immediate and punitive impact of mechanosensory disturbance on olfactory behaviour of larval Drosophila. Biol Open 3: 1005-1010.

*these publications refer to functional SPECT imaging which will be used in the next funding period.

Project B14

  • Caiazzo M, Dell'Anno MT, Dvoretskova E, Lazarevic D, Taverna S, Leo D, Sotnikova TD, Menegon A, Roncaglia P, Colciago G, Russo G, Carninci P, Pezzoli G, Gainetdinov RR, Gustincich S, Dityatev A*, Broccoli V* (2011) Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 476:224-227. *Co-senior authors.
  • Dityatev A, Seidenbecher CI, Schachner M (2010) Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain. Trends Neurosci 33: 503-512.
  • Frischknecht R, Heine M, Perrais D, Seidenbecher CI, Choquet D, Gundelfinger ED (2009) Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity. Nat Neurosci 12:897-904.
  • Happel MF, Niekisch H, Castiblanco Rivera LL, Ohl FW, Deliano M, Frischknecht R (2014) Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex. Proc Natl Acad Sci USA 111: 2800-2805
  • Kochlamazashvili G, Henneberger C, Bukalo O, Dvoretskova E, Senkov O, Lievens PM, Westenbroek R, Engel AK, Catterall WA, Rusakov DA, Schachner M, Dityatev A (2010) The extracellular matrix molecule hyaluronic acid regulates hippocampal synaptic plasticity by modulating postsynaptic L-type Ca2+ channels. Neuron 67:116-28.
  • Korotchenko S, Cingolani LA, Kuznetsova T, Bologna LL, Chiappalone M, Dityatev A (2014) Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates. Philos Trans R Soc Lond B Biol Sci. Special issue: Brain circuitry outside the synaptic cleft. 369 pii: 20140134.
  • Michaluk P, Mikasova L, Groc L, Frischknecht R, Choquet D, Kaczmarek L (2009) Matrix metalloproteinase-9 controls NMDA receptor surface diffusion through integrin beta1 signaling. J Neurosci 29:6007-6012.
  • Morellini F, Sivukhina E, Stoenica E, Oulianova E, Bukalo O, Jakovcevski I, Dityatev A., Irintchev A, Schachner M (2010) Improved reversal learning and working memory and enhanced reactivity to novelty in mice with enhanced GABAergic innervation in the dentate gyrus. Cereb Cortex 20:2712-2727.
  • Sakry, D., Neitz, A., Singh, J., Frischknecht, R., Marongiu, D., Biname, F., Perera, S.S., Endres, K., Lutz, B., Radyushkin, K., Trotter, J. & Mittmann, T. (2014) Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2. PLoS Biol, 12, e1001993.
  • Valenzuela JC, Heise C, Franken G, Singh J, Schweitzer B, Seidenbecher CI, Frischknecht R. Hyaluronan-based extracellular matrix under conditions of homeostatic plasticity. (2014) Philos Trans R Soc Lond B Biol Sci. 19;369(1654):20130606.

Project B15N

  • Appel M, Scholz C-J, Müller T, Dittrich M, König C, Bockstaller M, Oguz T, Khalili A, Antwi-Adjei E, Schauer T, Margulies C, Tanimoto H, Yarali A. (2015) Genome-wide association analyses point to candidate genes for electric shock avoidance in Drosophila melanogaster. Plos ONE 10: e0126986.
  • Diegelmann S, Preuschoff S, Appel M, Niewalda T, Gerber B, Yarali A (2013) Memory decay and susceptibility to amnesia dissociate punishment--from relief-learning. Biology Letters 9: 20121171.
  • Dieterich DC, Hodas JJ, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, Schuman EM (2010) In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nature neuroscience 13: 897-905.
  • Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proceedings of the National Academy of Sciences of the United States of America 103: 9482-9487.
  • Erdmann I, Marter K, Kobler O, Niehues S, Abele J, Müller A, Bussmann J, Storkebaum E, Ziv T, Thomas U, Dieterich DC. (2015-in press) Cell-selective labeling of proteomes in Drosophila melanogaster. Nat. Comm doi: 10.1038/ncomms8521
  • Hodas JJ, Nehring A, Hoche N, Sweredoski MJ, Pielot R, Hess S, Tirrell DA, Dieterich DC, Schuman EM (2012) Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT). Proteomics 12: 2464-2476.
  • Ngo JT, Champion JA, Mahdavi A, Tanrikulu IC, Beatty KE, Connor RE, Yoo TH, Dieterich DC, Schuman EM, Tirrell DA (2009) Cell-selective metabolic labeling of proteins. Nature chemical biology 5: 715-717.
  • Niehues S, Bussmann J, Steffes G, Erdmann I, Köhrer C, Sun L, Wagner M, Schäfer, K, Wang G, Koerdt SN, Stum M, RajBhandary U, Thomas U, Aberle H, Burgess R, Yang, XL, Dieterich DC, Storkebaum E. (2015-in press) Impaired protein translation in Drosophila models for Charot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat. Comm. doi: 10.1038/ncomms8520.
  • Yarali A, Gerber B (2010) A Neurogenetic Dissociation between Punishment-, Reward-, and Relief-Learning in Drosophila. Frontiers in Behavioural Neuroscience 4: 189.
  • Yarali A, Nehrkorn J, Tanimoto H, Herz AV (2012) Event timing in associative learning: from biochemical reaction dynamics to behavioural observations. PloS One 7: e32885.

Project B16N

  • Browning M, Behrens TE, Jocham G, O'Reilly JX, Bishop SJ (2015) Anxious individuals have difficulty learning causal statistics of aversive environments. Nat Neurosci 18: 590-596
  • Happel MFK, Deliano M, Handschuh J, Ohl FW (2014) Dopamine-modulated recurrent corticoefferent feedback in primary sensory cortex promotes detection of behaviorally relevant stimuli. J Neurosci 34: 1234-1247.
  • Happel MFK, Niekisch H, Castiblanco Rivera LL, Ohl FW, Deliano M, Frischknecht R (2014a) Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex. Proc Natl Acad Sci USA 111: 2800-2805
  • Happel MFK, Deliano M, Ohl FW (2015) Combined Shuttle-box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning. J. Vis. Exp. (), e53002, doi:10.3791/53002
  • Happel MFK, Jeschke M, Ohl FW (2010) Spectral integration in primary auditory cortex attributable to temporally precise convergence of thalamocortical and intracortical input. J Neurosci 30: 11114-11127.
  • Mylius J, Happel MFK, Gorkin AG, Huang Y, Scheich H, Brosch M (2014) Fast transformation from the dopaminergic ventral midbrain to the sensory cortex of awake primates; Brain Struct Funct, doi: 10.1007/s00429-014-0855-0.
  • Jocham G, Hunt LT, Near J, Behrens TE (2012) A mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex. Nat Neurosci 15: 960 -961
  • Jocham G, Klein TA, Ullsperger M (2014) Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonists. J Neurosci 34: 13151-13162.
  • Jocham G, Klein TA, Ullsperger M (2011) Dopamine-mediated reinforcement learning signals in the striatum and ventromedial prefrontal cortex underlie value-based choices. J Neurosci 31: 1606-1613.
  • Jocham G, Klein TA, Neumann J, von Cramon DY, Reuter M, Ullsperger M (2009) Dopamine DRD2 polymorphism alters reversal learning and associated neural activity. J Neurosci 29: 3695-3704.

Project B17N

  • Beer Z.+, Vavra P.+, Atucha E., Rentzing K., Heinze HJ and Sauvage MM. The memory for time and space differentially engages the proximal and distal parts of the hippocampal subfields CA1 and CA3. PLoS Biol 16(8): e2006100. https://doi.org/10.1371/journal.pbio.2006100.(IF: 9.16)
  • Eichenbaum H, Sauvage MM, Fortin N, Komorowski R, Lipton P. 2011. Towards a functional organization of episodic memory in the medial temporal lobe. Neurosci Biobehav Rev 36:1597-1608 (IF: 8.30)
  • Kabanova A, Pabst M, Lorkowski M, Braganza O, Boehlen A, Nikbakht N, Pothmann L, Vaswani AR, Musgrove R, Di Monte DA, Sauvage MM, Beck H, Blaess S. 2015. Function and developmental origin of a mesocortical inhibitory circuit. Nat Neurosci 18:872-82 (IF: 16.72)
  • Lux V, Masseck OA, Herlitze S, Sauvage MM. 2017. Optogenetic Destabilization of the Memory Trace in CA1: Insights into Reconsolidation and Retrieval Processes. Cereb cortex 27:841-85 (IF: 6.30) (Recommended by the "faculty of 1000")
  • Lux V, Kitsukawa T, Sauvage MM. 2016. Imaging a memory trace over half a life-time in the medial temporal lobe reveals a time-limited role of CA3 in retrieval. eLife 5:e11862 (IF: 7.77)
  • Nakamura N, Flasbeck V, Maingret N, Kitsukawa T, Sauvage MM. 2013. Proximodistal segregation of non-spatial information in CA3: preferential involvement of a proximal CA3-distal CA1 network in non-spatial recognition memory? J Neurosci 33:11506-14 (IF: 6.74)
  • Sauvage MM, Beer Z, Ho L, Eichenbaum H. 2010. The caudal medial entorhinal cortex: a selective role in recollectionbased recognition memory. J Neurosci 30:15695-15699 (IF: 5.99)
  • Sauvage MM, Fortin N, Owens C, Yonelinas AP, Eichenbaum H. 2008. Recognition memory: opposite effects of hippocampal damage on recollection and familiarity. Nat Neurosci 11:16-8 (highlighted in Nature Perspectives) (IF: 17.84)
  • Trossbach S, Bader V, Hecher V, Prikulis I, Pum M, Schäble S, de Souza Silva MA, Huston J, Su P, Ramsey A, Liu F, Massoud S,Boulat B, Chwiesko C, Sauvage MM, Lohr K, Stout K, Miller G, Weisshaupt A, Bauer A, Godsave S, Peters P, Bilzer T, Steiner T, Seeman P, Brandon N, Poschmann G, Stühler K, Müller-Schiffmann A and Korth C. 2015. Misassembly of full-length Disrupted-in-schizophrenia 1 (DISC1) protein is linked to altered dopamine homeostasis and behavioral deficits. Mol Psychiatr 21:1561-1572 (IF: 13.20)